发明申请
- 专利标题： Aryl-isoxazolo-4-yl-oxadiazole derivatives
- 专利标题（中）： 芳基异恶唑-4-基 - 恶二唑衍生物
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申请号： US11639695申请日： 2006-12-15
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公开(公告)号： US20070161686A1公开(公告)日： 2007-07-12
- 发明人: Bernd Buettelmann , Bo Han , Henner Knust , Andreas Koblet , Andrew Thomas
- 申请人： Bernd Buettelmann , Bo Han , Henner Knust , Andreas Koblet , Andrew Thomas
- 优先权： EP05112956.7 20051223
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; C07D413/02
摘要：
The present invention is concerned with isoxazol-4-yl-oxadiazole derivatives of formula wherein R1, R2, and R3, are as defined in the specification and pharmaceutically acceptable acid addition salts thereof. This class of compounds has high affinity and selectivity for GABA A α5 receptor binding sites and might be useful as cognitive enhancer or for the treatment of cognitive disorders like Alzheimer's disease.
公开/授权文献
- US07541372B2 Aryl-isoxazolo-4-yl-oxadiazole derivatives 公开/授权日：2009-06-02
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