发明申请
US20070179186A1 INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
有权
11-羟基脱氢酶脱氢酶1型酶的抑制剂
- 专利标题： INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
- 专利标题（中）： 11-羟基脱氢酶脱氢酶1型酶的抑制剂
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申请号： US11733636申请日： 2007-04-10
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公开(公告)号： US20070179186A1公开(公告)日： 2007-08-02
- 发明人: Jeffrey Rohde , Qi Shuai , James Link , Jyoti Patel , Jurgen Dinges , Bryan Sorensen , Hong Yong , Vince Yeh , Ravi Kurukulasuriya
- 申请人： Jeffrey Rohde , Qi Shuai , James Link , Jyoti Patel , Jurgen Dinges , Bryan Sorensen , Hong Yong , Vince Yeh , Ravi Kurukulasuriya
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/4015 ; C07D211/06
摘要：
The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme, The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
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