发明申请
US20070207138A1 S/O Type Pharmaceutical Preparation and Method for Producing the Same
审中-公开
S / O型药物制备及其制备方法
- 专利标题: S/O Type Pharmaceutical Preparation and Method for Producing the Same
- 专利标题(中): S / O型药物制备及其制备方法
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申请号: US11547090申请日: 2005-03-31
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公开(公告)号: US20070207138A1公开(公告)日: 2007-09-06
- 发明人: Masahiro Goto , Noriho Kamiya , Aklhiko Hirata , Takeru Fujii
- 申请人: Masahiro Goto , Noriho Kamiya , Aklhiko Hirata , Takeru Fujii
- 申请人地址: JP TOKUSHIMA-SHI, TOKUSHIMA
- 专利权人: ASPION CO., LTD.
- 当前专利权人: ASPION CO., LTD.
- 当前专利权人地址: JP TOKUSHIMA-SHI, TOKUSHIMA
- 优先权: JP2004-103347 20040331
- 国际申请: PCT/JP05/06812 WO 20050331
- 主分类号: A61K9/20
- IPC分类号: A61K9/20 ; A61K38/46 ; A61K38/47 ; A61K31/727 ; A61K31/405 ; A61K31/192
摘要:
The present invention provides a pharmaceutical preparation that significantly reduces leakage of a low-molecule medicine in a strong acidic environment, while allowing release of the low-molecule medicine in the enteric canal or the like which is in a weak acidic to neutral environment. The S/O type pharmaceutical preparation of the present invention is characterized in comprising a medicine-containing complex dissolved or dispersed in an oil phase, wherein the complex contains a mixture and a surfactant, the mixture is covered by the surfactant, and the mixture contains a hydrophilic low molecule medicine, and a hydrophilic medicine-leakage-suppressive protein and/or a medicine-leakage-suppressive polysaccharide.