发明申请
- 专利标题： Fused heterobicyclic kinase inhibitors
- 专利标题（中）： 融合的杂双环激酶抑制剂
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申请号： US11654814申请日： 2007-01-18
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公开(公告)号： US20070208053A1公开(公告)日： 2007-09-06
- 发明人: Lee Arnold , Xin Chen , Hanqing Dong , Andrew Garton , Mark Mulvihill , Colin Sambrook Smith , Gerard Thomas , Thomas Krulle , Jing Wang
- 申请人： Lee Arnold , Xin Chen , Hanqing Dong , Andrew Garton , Mark Mulvihill , Colin Sambrook Smith , Gerard Thomas , Thomas Krulle , Jing Wang
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; A61K31/4745
摘要：
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X5, X7, R1, and Q1 are defined herein, inhibit kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer. The compounds are also useful in the treatment of inflammation, allergy, asthma, disease and conditions of the immune system, disease and conditions of the nervous system, cardiovascular diseases, disease and conditions of the eye, dermatological diseases, osteoporosis, diabetes, multiple sclerosis, and infections.
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