发明申请
- 专利标题： Efficient drug screening for protein targets
- 专利标题（中）： 蛋白质靶标的高效药物筛选
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申请号： US11603473申请日： 2006-11-21
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公开(公告)号： US20070218475A1公开(公告)日： 2007-09-20
- 发明人: Philip Beachy , Anssi Taipale , James Chen
- 申请人： Philip Beachy , Anssi Taipale , James Chen
- 主分类号： C40B30/06
- IPC分类号： C40B30/06 ; C40B40/08 ; C40B40/10
摘要：
The methods of the invention allow extremely high throughput screening of chemicals against a large number of pharmacologically relevant targets. All of the pharmacologically relevant targets are expressed in cells, which are then screened against a fluorescently-tagged combinatorial library. Binding of the small molecules to the cells is then detected by fluorescence activated cell sorting or imaging.
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