发明申请
- 专利标题： PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES
- 专利标题（中）： 制备化合物和相关中间体的方法
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申请号： US11697379申请日： 2007-04-06
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公开(公告)号： US20070249823A1公开(公告)日： 2007-10-25
- 发明人: Vladimir Naddaka , Eyal Klopfer , Shady Saeed , Dionne Montvilisky , Oded Arad , Joseph Kaspi
- 申请人： Vladimir Naddaka , Eyal Klopfer , Shady Saeed , Dionne Montvilisky , Oded Arad , Joseph Kaspi
- 申请人地址： IL Bnei Brak
- 专利权人： Chemagis Ltd.
- 当前专利权人： Chemagis Ltd.
- 当前专利权人地址： IL Bnei Brak
- 主分类号： C07H19/00
- IPC分类号： C07H19/00
摘要：
The present invention provides novel intermediates, which preferably include 3-substituted, alkyl 2,2-difluoro-3-hydroxy-3-(2,2-dialkyldioxolan-4-yl)-propionate derivatives, and 3,5-disubstituted-2-deoxy-2,2-difluoro-1-oxo-D-ribose derivatives. The present invention also provides processes for producing such intermediates and processes for producing gemcitabine therewith.
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