发明申请
- 专利标题： Heteroaryl Piperidine Glycine Transporter Inhibitors
- 专利标题（中）： 杂芳基哌啶甘氨酸转运蛋白抑制剂
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申请号： US10593950申请日： 2005-03-23
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公开(公告)号： US20070254880A1公开(公告)日： 2007-11-01
- 发明人: Wesley Blackaby , Mark Duggan , David Hallett , George Hartman , Andrew Jennings , William Leister , Richard Lewis , Craig Lindsley , Elizabeth Naylor , Leslie Street , Yi Wang , David Wisnoski , Scott Wolkenberg , Zhijian Zhao
- 申请人： Wesley Blackaby , Mark Duggan , David Hallett , George Hartman , Andrew Jennings , William Leister , Richard Lewis , Craig Lindsley , Elizabeth Naylor , Leslie Street , Yi Wang , David Wisnoski , Scott Wolkenberg , Zhijian Zhao
- 国际申请： PCT/US05/09810 WO 20050323
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/5375 ; C07D211/06 ; C07D413/02
摘要：
The present invention is directed to pyridyl, pyridazinyl, pyrimidinyl and pyrazinyl piperidine compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergic or glutamatergic neurotransmission dysfunction and diseases in which the glycine transporter GlyT1 is involved.
公开/授权文献
- US07825135B2 Heteroaryl piperidine glycine transporter inhibitors 公开/授权日：2010-11-02
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