发明申请
US20070265312A1 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
失效
2-N {5 - [[4- [2-(甲基-2-吡啶基氨基)乙氧基]苯基]甲基] -2,4-噻唑烷二酮}丁二酸,制备方法和马来酸罗格列酮组合物
- 专利标题: 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
- 专利标题(中): 2-N {5 - [[4- [2-(甲基-2-吡啶基氨基)乙氧基]苯基]甲基] -2,4-噻唑烷二酮}丁二酸,制备方法和马来酸罗格列酮组合物
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申请号: US11430582申请日: 2006-05-09
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公开(公告)号: US20070265312A1公开(公告)日: 2007-11-15
- 发明人: Yehudit Dolitzky , Yoseph Avezov , Dina Spivak , Minutza Leibovici , Ben-Zion Solomon
- 申请人: Yehudit Dolitzky , Yoseph Avezov , Dina Spivak , Minutza Leibovici , Ben-Zion Solomon
- 专利权人: Teva Pharmaceutical Industries, Ltd.
- 当前专利权人: Teva Pharmaceutical Industries, Ltd.
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; C07D417/00
摘要:
Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
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