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![2-N-{5-[ [4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione) butanedioic acid, methods of preparation and compositions with rosiglitazone maleate](/abs-image/US/2010/04/01/US20100081695A1/abs.jpg.150x150.jpg)
1.发明申请2-N-{5-[ [4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione) butanedioic acid, methods of preparation and compositions with rosiglitazone maleate 审中-公开2-N- {5 - [[4- [2-（甲基-2-吡啶基氨基）乙氧基]苯基]甲基] -2,4-噻唑烷二酮）丁二酸，制备方法和马来酸罗格列酮组合物公开(公告)号：US20100081695A1
公开(公告)日：2010-04-01
申请号：US12592442
申请日：2009-11-24
IPC分类号： A61K31/4439 , B05D3/00 , C07D417/12 , A61P3/10
CPC分类号： C07D417/12
摘要： Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
摘要翻译： 公开了一种分离的下式的化合物，以及马来酸罗格列酮的改进的药物组合物的检测方法和使其最小化的方法。
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![2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate](/abs-image/US/2009/12/15/US07632841B2/abs.jpg.150x150.jpg)
2.发明授权2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate 失效2-N {5 - [[4- [2-（甲基-2-吡啶基氨基）乙氧基]苯基]甲基] -2,4-噻唑烷二酮}丁二酸，制备方法和马来酸罗格列酮组合物公开(公告)号：US07632841B2
公开(公告)日：2009-12-15
申请号：US11584311
申请日：2006-10-20
IPC分类号： A61K31/505 , A61K31/44
CPC分类号： C07D417/12
摘要： Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
摘要翻译： 公开了一种分离的下式的化合物，以及马来酸罗格列酮的改进的药物组合物的检测方法和使其最小化的方法。
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![2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate](/abs-image/US/2008/10/14/US07435741B2/abs.jpg.150x150.jpg)
3.发明授权2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate 失效2-N {5 - [[4- [2-（甲基-2-吡啶基氨基）乙氧基]苯基]甲基] -2,4-噻唑烷二酮}丁二酸，制备方法和马来酸罗格列酮组合物公开(公告)号：US07435741B2
公开(公告)日：2008-10-14
申请号：US11430582
申请日：2006-05-09
IPC分类号： A61K31/505 , A61K31/44
CPC分类号： C07D417/12
摘要： Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
摘要翻译： 公开了一种分离的下式的化合物，以及马来酸罗格列酮的改进的药物组合物的检测方法和使其最小化的方法。
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公开(公告)号：US20070020329A1
公开(公告)日：2007-01-25
申请号：US11333906
申请日：2006-01-17
IPC分类号： A61K9/20 , A61K31/5377
CPC分类号： A61K31/421 , A61K9/2004 , A61K9/2009 , A61K9/2018 , A61K9/2077 , A61K31/5377
摘要： A method of formulating linezolid to provide a pharmaceutical composition comprising linezolid wherein the linezolid is linezolid Form IV substantially free of linezolid Form II, a solid pharmaceutical composition comprising linezolid Form IV substantially free of linezolid Form II and povidone, methods of treating a condition responsive to linezolid in a patient comprising administering to the patient a solid pharmaceutical composition comprising linezolid form IV substantially free of linezolid Form II, and methods of treating a condition responsive to linezolid in a patient comprising administering to the patient a solid pharmaceutical composition comprising linezolid form IV and povidone.
摘要翻译： 一种配制利奈唑胺以提供包含利奈唑胺的药物组合物的方法，其中利奈唑胺是利奈唑胺基本上不含利奈唑胺的利奈唑胺形式II，包含基本上不含利奈唑胺形式II的利奈唑胺形式IV和聚维酮的固体药物组合物， 利奈唑胺在患者中包括向患者施用包含基本上不含利奈唑胺II型的利奈唑胺形式IV的固体药物组合物，以及治疗患者中对利奈唑胺有反应的病症的方法，包括向患者施用包含利奈唑胺形式IV的固体药物组合物和 聚维酮
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公开(公告)号：US20100143461A1
公开(公告)日：2010-06-10
申请号：US12633563
申请日：2009-12-08
申请人： Ben-Zion Solomon , Zvika Doani
发明人： Ben-Zion Solomon , Zvika Doani
CPC分类号： A61K9/0056 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1694 , A61K9/2018 , A61K9/4866 , A61K31/44 , A61K31/473
摘要： The present invention provides solid oral formulations of palonosetron or salts thereof.
摘要翻译： 本发明提供帕洛诺司琼或其盐的固体口服制剂。
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6.发明申请2-N butanedioic acid, methods of preparation and compositions with rosiglitazone maleate 失效2-N丁二酸，制备方法和马来酸罗格列酮组合物公开(公告)号：US20070265313A1
公开(公告)日：2007-11-15
申请号：US11584311
申请日：2006-10-20
IPC分类号： A61K31/44 , C07D417/00
CPC分类号： C07D417/12
摘要： Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
摘要翻译： 公开了一种分离的下式的化合物，以及马来酸罗格列酮的改进的药物组合物的检测方法和使其最小化的方法。
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![2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate](/abs-image/US/2007/11/15/US20070265312A1/abs.jpg.150x150.jpg)
7.发明申请2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate 失效2-N {5 - [[4- [2-（甲基-2-吡啶基氨基）乙氧基]苯基]甲基] -2,4-噻唑烷二酮}丁二酸，制备方法和马来酸罗格列酮组合物公开(公告)号：US20070265312A1
公开(公告)日：2007-11-15
申请号：US11430582
申请日：2006-05-09
IPC分类号： A61K31/44 , C07D417/00
CPC分类号： C07D417/12
摘要： Disclosed is an isolated compound of the formula: along with methods of detecting it and of minimizing it in improved pharmaceutical compositions of rosiglitazone maleate.
摘要翻译： 公开了一种分离的下式的化合物，以及马来酸罗格列酮的改进的药物组合物的检测方法和使其最小化的方法。
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