发明申请
US20070274949A1 Cd25 Dna Vaccines for Treating and Preventing T-Cell Mediated Diseases
审中-公开
用于治疗和预防T细胞介导的疾病的Cd25 Dna疫苗
- 专利标题： Cd25 Dna Vaccines for Treating and Preventing T-Cell Mediated Diseases
- 专利标题（中）： 用于治疗和预防T细胞介导的疾病的Cd25 Dna疫苗
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申请号： US10591558申请日： 2007-06-08
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公开(公告)号： US20070274949A1公开(公告)日： 2007-11-29
- 发明人: Irun Cohen , Avishai Mimran , Francisco Quintana , Felix Mor , Pnina Carmi
- 申请人： Irun Cohen , Avishai Mimran , Francisco Quintana , Felix Mor , Pnina Carmi
- 申请人地址： IL Rehovot 76100
- 专利权人： Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
- 当前专利权人： Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
- 当前专利权人地址： IL Rehovot 76100
- 国际申请： PCT/IL05/00273 WO
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K9/127
摘要：
Compositions comprising nucleic acids encoding the α chain of IL-2 receptor (IL-2Ra, CD25), homologs and fragment thereof, are effective in the treatment and prevention of T cell mediated pathologies. Methods are provided for enhancing anti-ergotypic T cell activity in a subject in need thereof, and for treating or preventing T cell mediated pathologies, such as autoimmune disease, inflammatory diseases and graft rejection.
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