发明申请
US20070292349A1 Itpks as Modifiers of the Igfr Pathway and Methods of Use
审中-公开
Itpks作为Igfr途径和使用方法的修饰符
- 专利标题: Itpks as Modifiers of the Igfr Pathway and Methods of Use
- 专利标题(中): Itpks作为Igfr途径和使用方法的修饰符
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申请号: US10587683申请日: 2005-01-27
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公开(公告)号: US20070292349A1公开(公告)日: 2007-12-20
- 发明人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , Lynn Bjerke , Timothy Heuer
- 申请人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , Lynn Bjerke , Timothy Heuer
- 申请人地址: US CA South San Francisco 94083-0511
- 专利权人: Exelixis, Inc.
- 当前专利权人: Exelixis, Inc.
- 当前专利权人地址: US CA South San Francisco 94083-0511
- 国际申请: PCT/US05/03560 WO 20050127
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; A61K49/00 ; G01N33/00 ; G01N33/53 ; A61P43/00
摘要:
Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.