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1.
公开(公告)号:US20070292349A1
公开(公告)日:2007-12-20
申请号:US10587683
申请日:2005-01-27
申请人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , Lynn Bjerke , Timothy Heuer
发明人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , Lynn Bjerke , Timothy Heuer
CPC分类号: C12Q1/34 , G01N2500/00
摘要: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
摘要翻译: 人MIGFR基因被鉴定为IGFR途径的调节剂,因此是与缺陷性IGFR功能相关的病症的治疗靶点。 提供了鉴定IGFR调节剂的方法,包括筛选调节MIGFR活性的药剂。
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公开(公告)号:US20070264268A1
公开(公告)日:2007-11-15
申请号:US10587253
申请日:2005-01-27
申请人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , HaiGuang Zhang , Timothy Heuer
发明人: Lori Friedman , Helen Francis-Lang , Annette Parks , Kenneth Shaw , HaiGuang Zhang , Timothy Heuer
IPC分类号: A61K39/00 , A61P35/00 , C12N5/06 , C12Q1/02 , C12Q1/34 , C12Q1/68 , G01N33/53 , G01N33/566 , G01N33/574
CPC分类号: C12Q1/34 , G01N2500/00
摘要: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
摘要翻译: 人MIGFR基因被鉴定为IGFR途径的调节剂,因此是与缺陷性IGFR功能相关的病症的治疗靶点。 提供了鉴定IGFR调节剂的方法,包括筛选调节MIGFR活性的药剂。
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