发明申请
US20070293530A1 SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS
审中-公开
磺酰胺和磺酰胺衍生物作为脱乙酰壳多糖酶抑制剂
- 专利标题： SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS
- 专利标题（中）： 磺酰胺和磺酰胺衍生物作为脱乙酰壳多糖酶抑制剂
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申请号： US11762874申请日： 2007-06-14
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公开(公告)号： US20070293530A1公开(公告)日： 2007-12-20
- 发明人: David Smil , Silvana Leit , Alain Ajamian , Martin Allan , Yves Chantigny , Robert Deziel , Eric Therrien , Amal Wahhab , Sukhdev Manku
- 申请人： David Smil , Silvana Leit , Alain Ajamian , Martin Allan , Yves Chantigny , Robert Deziel , Eric Therrien , Amal Wahhab , Sukhdev Manku
- 申请人地址： CA Montreal H4S 2A1
- 专利权人： METHYLGENE INC.
- 当前专利权人： METHYLGENE INC.
- 当前专利权人地址： CA Montreal H4S 2A1
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; A61K31/4745
摘要：
This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I), and racemic and scalemic mixtures, diastereomers and enantiomers thereof: or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt, prodrug or complex thereof, wherein Y, L, Z, W, M, Ra, Rb and Rc are as defined in the specification.
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