发明申请
- 专利标题: Methods for altering cellular susceptibility to infection
- 专利标题(中): 改变细胞感染易感性的方法
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申请号: US11478316申请日: 2006-06-28
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公开(公告)号: US20080003681A1公开(公告)日: 2008-01-03
- 发明人: Mahalaxmi Gita Bangera , Leroy E. Hood , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Robert Langer , Elizabeth A. Sweeney , Lowell L. Wood , Victoria Y.H. Wood
- 申请人: Mahalaxmi Gita Bangera , Leroy E. Hood , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Robert Langer , Elizabeth A. Sweeney , Lowell L. Wood , Victoria Y.H. Wood
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; C12N5/06
摘要:
Methods as described herein relate to altering the potential infectivity of a cell or cells. Included are methods for altering DNA of non-terminally differentiated cells in locations that inhibit the function of at least one CCR5 gene relative to an unaltered version of the gene and providing stimulus for differentiation of the altered cell.
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