发明申请
- 专利标题： Novel Receptor Antagonists and Their Methods of Use
- 专利标题（中）： 新型受体拮抗剂及其使用方法
-
申请号： US11772977申请日： 2007-07-03
-
公开(公告)号： US20080009541A1公开(公告)日： 2008-01-10
- 发明人: Laura Chambers , Robert Gleave , Stefan Senger , Daryl Walter
- 申请人： Laura Chambers , Robert Gleave , Stefan Senger , Daryl Walter
- 申请人地址： GB Greenford UB6 0NN
- 专利权人： GLAXO GROUP LIMITED
- 当前专利权人： GLAXO GROUP LIMITED
- 当前专利权人地址： GB Greenford UB6 0NN
- 优先权： GB0613473.8 20060706; GB0622825.8 20061115; GB0705263.2 20070319; GB0711439.0 20070613
- 主分类号： A61K31/401
- IPC分类号： A61K31/401 ; A61P25/00 ; A61P29/00 ; A61P43/00 ; C07D207/00
摘要：
The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.
公开/授权文献
- US07718693B2 Receptor antagonists and their methods of use 公开/授权日：2010-05-18
信息查询
IPC分类:
