摘要:
The present invention to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activit, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, Particularly Alzheimer's disease.
摘要:
In accordance with the invention, there is a method of forming a toner. The method can include blending two or more colorants to form a sample toner and forming a sample color specimen including a printed image comprising the sample toner. The method can further include comparing spectral distribution curves of the sample color specimen with that of a target color specimen including a target color and repeating the disclosed steps until acquiring a desired spectral match between the sample toner and the target color.
摘要:
The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
摘要:
The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
摘要:
In accordance with the invention, there is a method of forming a toner. The method can include blending two or more colorants to form a sample toner and forming a sample color specimen including a printed image comprising the sample toner. The method can further include comparing spectral distribution curves of the sample color specimen with that of a target color specimen including a target color and repeating the disclosed steps until acquiring a desired spectral match between the sample toner and the target color.
摘要:
The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
摘要:
The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.