Invention Application
- Patent Title: NOVEL APOPTOSIS PROTEINS
- Patent Title (中): 新型疫苗蛋白
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Application No.: US11739267Application Date: 2007-04-24
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Publication No.: US20080021202A1Publication Date: 2008-01-24
- Inventor: Ying Luo , Betty Huang , Mary Shen , Pei Yu
- Applicant: Ying Luo , Betty Huang , Mary Shen , Pei Yu
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C07K16/18
- IPC: C07K16/18

Abstract:
The present invention is directed to novel apoptosis polypeptides such as the Apop1, Apop2, and Apop3 proteins and related molecules which are involved in modulating apoptosis and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are method for identifying novel compositions which modulate the biological activity of Apop1, Apop2, and Apop3, and the use of such compositions in diagnosis and treatment of disease.
Public/Granted literature
- US07488805B2 Apoptosis proteins Public/Granted day:2009-02-10
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