发明申请
- 专利标题: Cancer-linked genes as targets for chemotherapy
- 专利标题(中): 癌症相关基因为化疗靶向
-
申请号: US11599845申请日: 2006-11-15
-
公开(公告)号: US20080025981A1公开(公告)日: 2008-01-31
- 发明人: Paul Young , Reinhard Ebner , Zoe Weaver , Jeffrey Strovel , Stephen Horrigan , Martin Shea , Bernd Weigle , Michael Rieger , Jennifer Rick , Colyn Cain
- 申请人: Paul Young , Reinhard Ebner , Zoe Weaver , Jeffrey Strovel , Stephen Horrigan , Martin Shea , Bernd Weigle , Michael Rieger , Jennifer Rick , Colyn Cain
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P35/00 ; C07K16/30 ; C12Q1/68
摘要:
Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with methods for assaying for potential antitumor agents based on their modulation of the expression of these cancer-related genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing cancer using the gene sequences as well as the polypeptide sequences.
信息查询