Invention Application
- Patent Title: CHIMERIC AND HUMANIZED ANTIBODIES TO alpha5beta1 INTEGRIN THAT MODULATE ANGIOGENESIS
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Application No.: US11840871Application Date: 2007-08-17
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Publication No.: US20080026033A1Publication Date: 2008-01-31
- Inventor: Vanitha Ramakrishnan , David Powers , Dale Johnson , Ursula Jeffry
- Applicant: Vanitha Ramakrishnan , David Powers , Dale Johnson , Ursula Jeffry
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61P27/02 ; C12N5/06 ; C12N5/08
Abstract:
The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
Public/Granted literature
- US08017116B2 Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis Public/Granted day:2011-09-13
Information query
