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    Methods of production and use of anti-integrin antibodies for the control of tissue granulation
    5.
    发明申请
    Methods of production and use of anti-integrin antibodies for the control of tissue granulation 审中-公开
    抗整联蛋白抗体的生产和使用方法，用于控制组织造粒

    公开(公告)号：US20050002930A1

    公开(公告)日：2005-01-06

    申请号：US10818068

    申请日：2004-04-02

    申请人： Dale Johnson ,  Ursula Jeffry

    发明人： Dale Johnson ,  Ursula Jeffry

    IPC分类号： A61P27/02 ,  C07K16/28 ,  A61K39/395

    CPC分类号： C07K16/2842 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/56

    摘要： The present invention provides methods that enable the user to identify inhibitors of tissue granulation in and around a wound site, thereby limiting excessive scar formation as the wounded tissue heals. The some granulation inhibitors identified using the methods of the invention inhibit granulation in and around a wound site up to five fold, with a corresponding decrease in the formation of scar tissue when tested on retinal injuries. Granulation inhibitors that can be identified using the methods of the present invention include antibodies, peptides, nucleic acids (aptamers), and non-peptide small molecules.

    摘要翻译： 本发明提供了使用户能够鉴定伤口部位内和周围的组织造粒抑制剂的方法，从而限制伤口组织愈合时的过度瘢痕形成。 使用本发明的方法鉴定的一些造粒抑制剂在伤口部位及其周围抑制造粒至多达五倍，并且在对视网膜损伤进行测试时相应地减少瘢痕组织的形成。 可以使用本发明的方法鉴定的造粒抑制剂包括抗体，肽，核酸（适配体）和非肽小分子。

    LAYOUT CLIP AND METHOD OF USE
    7.
    发明申请
    LAYOUT CLIP AND METHOD OF USE 有权
    布局剪辑和使用方法

    公开(公告)号：US20090064513A1

    公开(公告)日：2009-03-12

    申请号：US11851491

    申请日：2007-09-07

    申请人： Dale Johnson

    发明人： Dale Johnson

    IPC分类号： B44D3/38

    CPC分类号： G01C15/06 ,  Y10T24/39

    摘要： A layout clip and method comprises a clip body having a channel formed therein which frictionally engages a string that is secured to a layout member that is placed to define a future structure. The layout clip has a gripping portion and is marked to indicate a structure layout position such as a wall etc. The clip has a layout mark on at least one surface. The layout clips are color coded to represent different service items such as plumbing lines or electrical runs. One embodiment includes an elongated gripping portion to aid in placing and removing the clip. A line clip method comprises locating and securing a string that corresponds to a structure such as a wall, pole or fence etc.; then securing a clip along the string to locate where a fixture or other component will be installed. The clips are removable and reusable.

    摘要翻译： 布局夹和方法包括具有形成在其中的通道的夹子主体，其摩擦地接合固定到布置构件的串，所述布局构件被放置以限定未来结构。 布置夹具具有夹持部分并被标记以指示诸如墙壁等的结构布局位置。夹具在至少一个表面上具有布局标记。 布局剪辑被颜色编码以表示不同的服务项目，例如管道线或电气运行。 一个实施例包括细长的抓握部分，以帮助放置和移除夹子。 线夹方法包括定位和固定对应于诸如墙壁，杆或围栏等结构的弦; 然后沿着弦固定一个夹子，以找到将要安装夹具或其他部件的位置。 剪辑是可拆卸的和可重复使用的。

    Quick disconnect nozzle assembly
    8.
    发明授权
    Quick disconnect nozzle assembly 有权
    快速断开喷嘴总成

    公开(公告)号：US06244527B1

    公开(公告)日：2001-06-12

    申请号：US09492024

    申请日：2000-01-26

    申请人： Gerald P. Ferrazza ,  Evelyn Celio ,  Dale Johnson

    发明人： Gerald P. Ferrazza ,  Evelyn Celio ,  Dale Johnson

    IPC分类号： B05B100

    CPC分类号： B05B15/65

    摘要： A quick disconnect spray nozzle assembly having a nozzle body for connection to a fluid supply source and a removable and replaceable spray tip. The spray tip carries an externally mounted, elongated, tubular seal and biasing member which has an asymmetrical design, including an enlarged cylindrical downstream end and a rounded upstream end, configured for effecting radial and axial sealing forces upon engagement with seal a seating cavity in the nozzle body. The spray tip further includes radial camming and locking lugs having planar camming, detent, and locking surfaces which cooperate with the nozzle body for drawing the spray tip into mounted engagement, with the elongated sealing member interposed therebetween, as an incident to quick turn rotation of the spray tip and without the necessity for manually forcing the spray tip against the seal and biasing member.

    摘要翻译： 一种快速断开喷嘴组件，其具有用于连接到流体供应源的喷嘴体和可移除和可更换的喷雾尖端。 喷嘴带有外部安装的，细长的管状密封和偏置构件，其具有不对称设计，包括扩大的圆柱形下游端和圆形的上游端，构造成用于在接合时在径向和轴向密封力的作用下密封座腔 喷嘴体。 喷嘴还包括具有平面凸轮，止动和锁定表面的径向凸轮和锁定凸耳，其与喷嘴体配合，用于将喷嘴尖端插入安装的接合中，细长的密封构件插入其间，作为快速旋转的事件 喷嘴并且不需要手动地迫使喷嘴抵靠密封件和偏置构件。

    Grain loss monitor
    9.
    发明授权
    Grain loss monitor 失效
    粮食损失监测

    公开(公告)号：US4036065A

    公开(公告)日：1977-07-19

    申请号：US685282

    申请日：1976-05-11

    申请人： William P. Strelioff ,  William S. Elliott ,  Dale Johnson

    发明人： William P. Strelioff ,  William S. Elliott ,  Dale Johnson

    IPC分类号： A01D41/127 ,  G01N29/04 ,  G01P5/24 ,  G01P13/00 ,  G01N29/00

    CPC分类号： A01D41/1273 ,  G01N29/046 ,  G01P13/0073 ,  G01P5/24 ,  G01N2291/02408

    摘要： A percentage of the grain lost is sampled constantly by sensors at locations across the rear of the sieve of a combine and the sound of the grain kernels striking the sensors is picked up by a microphone, amplified, filtered and fed to a ratio computing device which calculates the total grain loss from the sampling and displays same on a meter. A further sensor samples grain passing through the rear portion of a straw walker of a combine as this bears a direct relationship to the quantity of grain passing over the end of the walker. It can therefore be used to calculate the grain loss over the end of the walker. Once again the sound of the grain kernels striking the sensor is picked up by a microphone, amplified, filtered and fed to a ratio computing device which calculates the grain loss over the end of the walker and displays same on the meter. A switching device enables the total of the grain losses to be calculated from the two sensors by means of a summation device to which both sensor signals are connected. This switching device also enables the operator to weed out the grain loss over the sieve or the grain loss over the walker thus enabling him to determine where adjustments are required.

    摘要翻译： 谷物损失的百分比通过传感器在组合筛的后部的位置不断地进行采样，并且麦克风撞击传感器的声音由麦克风拾取，被放大，滤波并馈送到比率计算装置，比率计算装置 计算采样中的总谷物损失，并在仪表上显示相同的数据。 进一步的传感器对通过组合的吸管行走器后部的颗粒进行采样，因为这与经过助行器末端的颗粒数量成直接关系。 因此，它可用于计算步行者末端的谷物损失。 再次，麦克风撞击传感器的声音由麦克风拾取，放大，滤波并馈送到比例计算装置，该比率计算装置计算步行器末端的谷物损失并在米上显示相同的谷物损失。 开关装置使得能够通过两个传感器信号连接的求和装置从两个传感器计算总的谷物损失。 该开关装置还使得操作者能够清除筛子上的谷物损失或在步行者上的粮食损失，从而使得他能够确定需要调整的位置。