发明申请
- 专利标题: COLD MENTHOL RECEPTOR-1 ANTAGONISTS
- 专利标题(中): 冷门受体-1拮抗剂
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申请号: US11746318申请日: 2007-05-09
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公开(公告)号: US20080027029A1公开(公告)日: 2008-01-31
- 发明人: Raymond Colburn , Scott Dax , Christopher Flores , Jay Matthews , Ning Qin , Laura Reany , Christopher Teleha , Mark Youngman
- 申请人: Raymond Colburn , Scott Dax , Christopher Flores , Jay Matthews , Ning Qin , Laura Reany , Christopher Teleha , Mark Youngman
- 主分类号: A61K31/67
- IPC分类号: A61K31/67 ; A61K31/665 ; A61K31/675 ; A61P25/00 ; A61P29/00 ; A61P9/00 ; A61P9/12 ; C07D495/00 ; C07F9/572 ; C07F9/655 ; C07F9/6553
摘要:
The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.
公开/授权文献
- US07897781B2 Cold menthol receptor-1 antagonists 公开/授权日:2011-03-01
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