Invention Application
US20080038775A1 Method of Synthesizing and Purifying Dkk Proteins and Dkk Proteins Obtained Thereby
失效
合成和纯化由此得到的Dkk蛋白质和Dkk蛋白质的方法
- Patent Title: Method of Synthesizing and Purifying Dkk Proteins and Dkk Proteins Obtained Thereby
- Patent Title (中): 合成和纯化由此得到的Dkk蛋白质和Dkk蛋白质的方法
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Application No.: US10593089Application Date: 2005-03-23
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Publication No.: US20080038775A1Publication Date: 2008-02-14
- Inventor: Kristina Allen , Anthony Anisowicz , Wei Chen , Girija Krishnamurthy , Matthew Olson
- Applicant: Kristina Allen , Anthony Anisowicz , Wei Chen , Girija Krishnamurthy , Matthew Olson
- Applicant Address: US NJ MADISON US MA WALTHAM
- Assignee: WYETH,OSCIENT PHARMACEUTICALS CORPORATION
- Current Assignee: WYETH,OSCIENT PHARMACEUTICALS CORPORATION
- Current Assignee Address: US NJ MADISON US MA WALTHAM
- International Application: PCT/US05/10001 WO 20050323
- Main IPC: C12P21/04
- IPC: C12P21/04 ; C07K14/00
Abstract:
The invention relates to a novel method of inexpensively synthesizing large quantities of an essentially pure, biologically active, glycosylated Dkk protein, including mammalian and human Dkk proteins (e.g., human Dkk1). The invention further relates to the synthetically produced essentially purified, glycosylated and biologically active Dkk protein, and the characteristics of the protein.
Public/Granted literature
- US07867699B2 Method of synthesizing and purifying Dkk proteins and Dkk proteins obtained thereby Public/Granted day:2011-01-11
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