发明申请
US20080058327A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS
有权
作为AKT蛋白激酶抑制剂的PYRIMIDYL CYCLOPENTANES
- 专利标题： PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS
- 专利标题（中）： 作为AKT蛋白激酶抑制剂的PYRIMIDYL CYCLOPENTANES
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申请号： US11773946申请日： 2007-07-05
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公开(公告)号： US20080058327A1公开(公告)日： 2008-03-06
- 发明人: Ian Mitchell , James Blake , Rui Xu , Nicholas Kallan , Dengming Xiao , Keith Spencer , Josef Bencsik , Eli Wallace , Stephen Schlachter , Anna Banka , Jun Liang , Brian Safina , Jun Li , Christine Chabot
- 申请人： Ian Mitchell , James Blake , Rui Xu , Nicholas Kallan , Dengming Xiao , Keith Spencer , Josef Bencsik , Eli Wallace , Stephen Schlachter , Anna Banka , Jun Liang , Brian Safina , Jun Li , Christine Chabot
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/535 ; A61P43/00 ; C07D211/00 ; C07D239/70
摘要：
The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
公开/授权文献
- US08003651B2 Pyrimidyl cyclopentanes as AKT protein kinase inhibitors 公开/授权日：2011-08-23
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