发明申请
US20080064054A1 FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY
审中-公开
荧光共振能量转移（FRET）测定螯合性毒素活性
- 专利标题： FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY
- 专利标题（中）： 荧光共振能量转移（FRET）测定螯合性毒素活性
-
申请号： US11753304申请日： 2007-05-24
-
公开(公告)号： US20080064054A1公开(公告)日： 2008-03-13
- 发明人: Ester Fernandez-Salas , Kei Roger Aoki , Lance Steward
- 申请人： Ester Fernandez-Salas , Kei Roger Aoki , Lance Steward
- 主分类号： C12N1/02
- IPC分类号： C12N1/02 ; C07K14/00 ; C12N15/00 ; C12N15/11 ; C12N5/06
摘要：
Clostridial toxin substrates comprising a fluorescent donor, an acceptor, a Clostridial toxin recognition sequence including a cleavage site and a membrane targeting domain; methods for determining the activity of a Clostridial toxin from a test sample using such Clostridial toxin substrates; cell compositions comprising such Clostridial toxin substrates and a Clostridial toxin receptor; and methods for determining the activity of a Clostridial toxin from a test sample using such cell compositions.
信息查询
IPC分类:
