发明申请
- 专利标题: PYRAZOLE-AMINE COMPOUNDS USEFUL AS KINASE INHIBITORS
- 专利标题(中): 吡唑胺化合物作为激酶抑制剂有用
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申请号: US11931309申请日: 2007-10-31
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公开(公告)号: US20080108626A1公开(公告)日: 2008-05-08
- 发明人: Alaric Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert Moquin , Stephen Wrobleski
- 申请人: Alaric Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert Moquin , Stephen Wrobleski
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; C07D231/12 ; A61K31/415 ; C07D413/12 ; A61K31/42 ; C07D413/14 ; A61K31/4439 ; C07D401/04
摘要:
The present invention provides pyrazole derived compounds of formula (I) useful for treating p38 kinase-associated conditions, where G, X, R1, R2, R3, R4, R5, R6 and m are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
公开/授权文献
- US07390810B2 Pyrazole-amine compounds useful as kinase inhibitors 公开/授权日:2008-06-24