发明申请
US20080113005A1 Composition Comprising an Extract of Gramineae Plant for the Prevention and Treatment of Ischemic Diseases and Degenerative Brain Diseases and the Use Thereof
审中-公开
包含禾本科植物提取物的组合物，用于预防和治疗缺血性疾病和退行性脑疾病及其应用
- 专利标题： Composition Comprising an Extract of Gramineae Plant for the Prevention and Treatment of Ischemic Diseases and Degenerative Brain Diseases and the Use Thereof
- 专利标题（中）： 包含禾本科植物提取物的组合物，用于预防和治疗缺血性疾病和退行性脑疾病及其应用
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申请号： US11813285申请日： 2006-01-04
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公开(公告)号： US20080113005A1公开(公告)日： 2008-05-15
- 发明人: Jong Won Lee , Ki-Chul Hwang , Hyung Soo Han , Sun Ha Lim , Hyeong-Kyu Lee , Sang Hyuk Lee , Kyu Won Kim , Hyung Oh Jun , Hyun Jeong Kim , In-Seon Lee , Chae Ha Yang
- 申请人： Jong Won Lee , Ki-Chul Hwang , Hyung Soo Han , Sun Ha Lim , Hyeong-Kyu Lee , Sang Hyuk Lee , Kyu Won Kim , Hyung Oh Jun , Hyun Jeong Kim , In-Seon Lee , Chae Ha Yang
- 申请人地址： KR Daegu KR Daegu
- 专利权人： HYPOXI CO., LTD.,SUN MOK INSTITUTE EDUCATION FOUNDATION
- 当前专利权人： HYPOXI CO., LTD.,SUN MOK INSTITUTE EDUCATION FOUNDATION
- 当前专利权人地址： KR Daegu KR Daegu
- 优先权： KR10-2005-0000330 20050104; KR10-2005-0135745 20051230
- 国际申请： PCT/KR06/00027 WO 20060104
- 主分类号： A61K36/899
- IPC分类号： A61K36/899 ; A61K9/00 ; A61P25/28
摘要：
The present invention relates to a composition comprising extracts of Gramineae plant that improves cell viability under hypoxic conditions by inhibiting apoptosis. Thus, the extract of Triticum aestivum L., one of the Gramineae plant, of the present invention, in particular, prevents damage of brain, heart and kidney in animal models of ischemic diseases, and it also improves memory in an animal model of Alzheimer's disease. Therefore, a composition comprising extracts of Gramineae can be used as therapeutic agents or health care foods for preventing and treating ischemic diseases and degenerative brain diseases.
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