The invention relates to novel amphoteric polysaccharide compounds containing sulfonate function(s) corresponding to the formula (I) in which P represents a polysaccharide chain; X, Y and Z each represent a linear or branched, saturated or unsaturated, optionally hydroxylated C1-C12 divalent hydrocarbon-based group optionally comprising at least one ether and/or amine function in the hydrocarbon-based chain, or a group —Si(R)2—[O—Si(R)2]q-A-; r is 0 or 1; An represents an anionic group chosen from formula (II) CAT represents a quaternary ammonium group or a cationic polymer chain obtained by grafting and polymerization of ethylenic monomers bearing a quaternary ammonium function, Sulfo represents a sulfonic or sulfonate group; and n, m and p are such that the total degree of substitution of the polysaccharide does not exceed 2. The invention also relates to compositions comprising them and to their use in cosmetics.