Invention Application
- Patent Title: NEW SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF
- Patent Title (中): MDM2的新型小分子抑制剂及其用途
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Application No.: US11848089Application Date: 2007-08-30
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Publication No.: US20080125430A1Publication Date: 2008-05-29
- Inventor: Shaomeng Wang , Dongguang Qin , Jiangyong Chen , Shanghai Yu
- Applicant: Shaomeng Wang , Dongguang Qin , Jiangyong Chen , Shanghai Yu
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; C07D209/96 ; A61K31/407 ; C07D265/30 ; A61K31/445 ; A61P35/00 ; C07D211/06 ; C07D241/04 ; A61K31/497
Abstract:
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
Public/Granted literature
- US07737174B2 Indole inhibitors of MDM2 and the uses thereof Public/Granted day:2010-06-15
Information query
IPC分类:
