Invention Application
US20080125514A1 AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS 有权
氨基酸共聚物和与共聚物包衣的医疗装置

  • Patent Title: AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS
  • Patent Title (中): 氨基酸共聚物和与共聚物包衣的医疗装置
  • Application No.: US11942705
    Application Date: 2007-11-19
  • Publication No.: US20080125514A1
    Publication Date: 2008-05-29
  • Inventor: Stephen Pacetti
  • Applicant: Stephen Pacetti
  • Applicant Address: US IL Abbott Park
  • Assignee: ABBOTT LABORATORIES
  • Current Assignee: ABBOTT LABORATORIES
  • Current Assignee Address: US IL Abbott Park
  • Main IPC: A61F2/02
  • IPC: A61F2/02
AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS
Abstract:
Biocompatible polymers are manufactured to include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers. The amino acid mimetic monomers are selected to mimic the side chain of the amino acids asparagine or glutamine. The amino acid mimetic monomer can be a methacryloyl or acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide, or glycinamide. These amide functional groups offer the advantage of moderate hydrophilicity with little chemical reactivity. The amino acid mimetic monomer can be copolymerized with one or more hydrophobic acrylate monomers to obtain desired coating properties.
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