发明申请
US20080132426A1 DISCRETE NANO-TEXTURED STRUCTURES IN BIOMOLECULAR ARRAYS, AND METHOD OF USE
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生物分子阵列中的分离的纳米结构和使用方法
- 专利标题: DISCRETE NANO-TEXTURED STRUCTURES IN BIOMOLECULAR ARRAYS, AND METHOD OF USE
- 专利标题(中): 生物分子阵列中的分离的纳米结构和使用方法
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申请号: US12028767申请日: 2008-02-08
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公开(公告)号: US20080132426A1公开(公告)日: 2008-06-05
- 发明人: Mark Whitney Hart , Ho-Cheol Kim , Robert Dennis Miller , Gregory Michael Wallraff
- 申请人: Mark Whitney Hart , Ho-Cheol Kim , Robert Dennis Miller , Gregory Michael Wallraff
- 申请人地址: US NY Armonk
- 专利权人: INTERNATIONAL BUSINESS MACHINES CORPORATION
- 当前专利权人: INTERNATIONAL BUSINESS MACHINES CORPORATION
- 当前专利权人地址: US NY Armonk
- 主分类号: C40B40/00
- IPC分类号: C40B40/00
摘要:
A biomolecular array includes a substrate across which is distributed an array of discrete regions of a porous substance formed from a porogen-containing organosilicate material. The porous substance is designed to bind chemical targets useful in biotechnology applications, such as gene expression, protein, antibody, and antigen experiments. The regions are preferably optically isolated from each other and may be shaped to enhance detection of optical radiation emanating from the porous substance, e.g., as a result of irradiation of the regions with ultraviolet light. The discrete regions may be configured as microscopic wells within the substrate, or they may reside on top of the substrate in the form of microscopic mesas.