发明申请
- 专利标题: Guanidine Compound and Asymmetric Reaction Using the Same
- 专利标题(中): 胍化合物和使用其的不对称反应
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申请号: US10589814申请日: 2005-02-09
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公开(公告)号: US20080154036A1公开(公告)日: 2008-06-26
- 发明人: Masahiro Terada , Hitoshi Ube , Shigeko Yokoyama , Hideo Shimizu
- 申请人: Masahiro Terada , Hitoshi Ube , Shigeko Yokoyama , Hideo Shimizu
- 优先权: JP2004-041181 20040218
- 国际申请: PCT/JP05/01943 WO 20050209
- 主分类号: C07D223/14
- IPC分类号: C07D223/14
摘要:
A guanidine compound having a biaryl skeleton represented by the following formula (1), which is useful as a catalyst for various asymmetric reactions. (wherein R1, R2 and R3 each independently represent a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); R4 to R15 each independently represent a hydrogen atom, a hydrocarbon group optionally having substituent(s), a heterocyclic group optionally having substituent(s), a hydroxy group, an alkoxy group optionally having substituent(s), an aryloxy group optionally having substituent(s), an acyl group, an alkoxycarbonyl group optionally having substituent(s), an aryloxycarbonyl group optionally having substituent(s), a carbamoyl group optionally having substituent(s), an alkylthiocarbonyl group optionally having substituent(s), an arylthiocarbonyl group optionally having substituent(s), a carboxyl group, an alkylthio group optionally having substituent(s), an arylthio group optionally having substituent(s), an amino group or a substituted amino group, or a substituted silyl group; or in any combination of R1 to R15, these substituents may be taken together to form a ring; and X1 to X8 represent a hydrogen atom or a nitrogen atom, provided that, in the case of a nitrogen atom, there is no substituent on X1 to X8.
公开/授权文献
- US07781425B2 Guanidine compound and asymmetric reaction using the same 公开/授权日:2010-08-24
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