发明申请
- 专利标题： MARKs as Modifiers of the p53 Pathway and Methods of Use
- 专利标题（中）： 标记作为p53途径的修饰物和使用方法
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申请号： US11627976申请日： 2007-01-28
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公开(公告)号： US20080166709A1公开(公告)日： 2008-07-10
- 发明人: Lori Friedman , Gregory D. Plowman , Marcia Belvin , Helen Francis-Lang , Danxi Li , Roel P. Funke , Mario N. Lioubin
- 申请人： Lori Friedman , Gregory D. Plowman , Marcia Belvin , Helen Francis-Lang , Danxi Li , Roel P. Funke , Mario N. Lioubin
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS, INC.
- 当前专利权人： EXELIXIS, INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N5/00
摘要：
Human MARK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of MARK are provided.
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