发明申请
- 专利标题: Therapeutic and diagnostic proteins comprising a SOCS box
- 专利标题(中): 包括SOCS盒的治疗和诊断蛋白质
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申请号: US11977132申请日: 2007-10-23
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公开(公告)号: US20080166730A1公开(公告)日: 2008-07-10
- 发明人: Douglas J. Hilton , Warren S. Alexander , Elizabeth M. Viney , Tracy A. Willson , Rachael T. Richardson , Robyn Starr , Sandra E. Nicholson , Donald Metcalf , Nicos A. Nicola
- 申请人: Douglas J. Hilton , Warren S. Alexander , Elizabeth M. Viney , Tracy A. Willson , Rachael T. Richardson , Robyn Starr , Sandra E. Nicholson , Donald Metcalf , Nicos A. Nicola
- 申请人地址: AU Parkville
- 专利权人: The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人: The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人地址: AU Parkville
- 优先权: AUPO3384/96 19961101; AUPO5117/97 19970214; AUPCT/AU97/00729 19971031
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention relates generally to therapeutic and diagnostic agents. More particularly, the present invention provides therapeutic molecules capable of modulating signal transduction such as but not limited to cytokine-mediated signal transduction. The molecules of the present invention are useful, therefore, in modulating cellular responsiveness to cytokines as well as other mediators of signal transduction such as endogenous or exogenous molecules, antigens, microbes and microbial products, viruses or components thereof, ions, hormones and parasites.
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