发明申请
- 专利标题： Mitotic Kinesin Inhibitors
- 专利标题（中）： 有丝分裂驱动蛋白抑制剂
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申请号： US11883507申请日： 2006-02-06
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公开(公告)号： US20080182843A1公开(公告)日： 2008-07-31
- 发明人: Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , Lou Anne Neilson , David B. Whitman
- 申请人： Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , Lou Anne Neilson , David B. Whitman
- 国际申请： PCT/US06/04214 WO 20060206
- 主分类号： A61K31/4162
- IPC分类号： A61K31/4162 ; C07D405/04 ; A61K31/5377 ; A61P35/00 ; C07D413/14
摘要：
The present invention relates to tricyclic pyrazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US07595337B2 Mitotic kinesin inhibitors 公开/授权日：2009-09-29
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