发明申请
- 专利标题: Array and Hybridization Method
- 专利标题(中): 阵列和杂交方法
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申请号: US11794811申请日: 2006-01-16
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公开(公告)号: US20080200347A1公开(公告)日: 2008-08-21
- 发明人: Yasuko Yoshida , Kazunari Yamada , Kousuke Niwa
- 申请人: Yasuko Yoshida , Kazunari Yamada , Kousuke Niwa
- 申请人地址: JP NAGOYA-CITY
- 专利权人: NGK INSULATORS, LTD.
- 当前专利权人: NGK INSULATORS, LTD.
- 当前专利权人地址: JP NAGOYA-CITY
- 国际申请: PCT/JP2006/300431 WO 20060116
- 主分类号: C40B40/06
- IPC分类号: C40B40/06 ; C40B50/08 ; C40B50/14 ; C40B60/14
摘要:
The present invention provides a hybridization method suited for using a signal probe. An array of the present invention comprises: a substrate; a nucleic acid probe that is fixed to the substrate and is hybridized with a sample to have a signal change; and at least one cavity that is filled with a specific liquid containing the sample and causing the hybridization of the nucleic acid probe with the sample. The array in this arrangement effectively enhances the reproducibility and the efficiency of hybridization with the signal probe.
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