Invention Application
US20080200454A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
审中-公开
碳氢化合物的联苯四唑 - 吡唑并吡啶调节剂
- Patent Title: CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
- Patent Title (中): 碳氢化合物的联苯四唑 - 吡唑并吡啶调节剂
-
Application No.: US12031010Application Date: 2008-02-14
-
Publication No.: US20080200454A1Publication Date: 2008-08-21
- Inventor: Michael K. Ameriks , Frank U. Axe , James P. Edwards , Cheryl A. Grice , Hui Cai , Elizabeth Ann Gleason , Steven P. Meduna , Kevin L. Tays , John J. M. Wiener , Alvah T. Wickboldt
- Applicant: Michael K. Ameriks , Frank U. Axe , James P. Edwards , Cheryl A. Grice , Hui Cai , Elizabeth Ann Gleason , Steven P. Meduna , Kevin L. Tays , John J. M. Wiener , Alvah T. Wickboldt
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61P37/00 ; A61P29/00 ; A61P1/00 ; A61P25/00 ; A61P35/00 ; A61K31/496 ; A61K31/541 ; A61K31/55 ; A61P17/00 ; A61P3/10 ; A61P11/00 ; C07D471/04 ; A61K31/53
Abstract:
Carbon-linked tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
Information query
IPC分类:
