公开(公告)号：US08762806B2

公开(公告)日：2014-06-24

申请号：US13120878

申请日：2009-09-15

Applicant: Po Shin Francois Chin ,  Zhao Hui Cai

Inventor： Po Shin Francois Chin ,  Zhao Hui Cai

IPC: H03M13/00 ,  H04L1/18 ,  G11C29/00

CPC classification number: H03M13/116 ,  H03M13/114

Abstract: A decoding circuit including a data buffer comprises a plurality of storage elements for storing data symbols, a processing circuit comprising a plurality of inputs and outputs, wherein the processing circuitry is configured to process data symbols received via the plurality of inputs and outputs. First and second decoding parameters are determined by a decoding rule and wherein the first and the second decoding parameters are not changed throughout the decoding process.

Abstract translation: 包括数据缓冲器的解码电路包括用于存储数据符号的多个存储元件，包括多个输入和输出的处理电路，其中所述处理电路经配置以处理经由所述多个输入和输出接收的数据符号。 第一和第二解码参数由解码规则确定，并且其中第一和第二解码参数在整个解码过程中不改变。

公开(公告)号：US20110160452A1

公开(公告)日：2011-06-30

申请号：US13043420

申请日：2011-03-08

Applicant: Hui Cai ,  Frank Chavez ,  James P. Edwards ,  Anne E. Fitzgerald ,  Jing Liu ,  Neelakandha S. Mani ,  Danielle K. Neff ,  Michele C. Rizzolio ,  Brad M. Savall ,  Deborah M. Smith ,  Jennifer D. Venable ,  Jianmai Wei ,  Ronald L. Wolin

Inventor： Hui Cai ,  Frank Chavez ,  James P. Edwards ,  Anne E. Fitzgerald ,  Jing Liu ,  Neelakandha S. Mani ,  Danielle K. Neff ,  Michele C. Rizzolio ,  Brad M. Savall ,  Deborah M. Smith ,  Jennifer D. Venable ,  Jianmai Wei ,  Ronald L. Wolin

IPC: C07D403/04 ,  C07D401/04 ,  C07D403/14 ,  C07D498/04

CPC classification number: C07D498/04 ,  C07D239/48 ,  C07D239/70 ,  C07D239/95 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/14 ,  C07D471/04 ,  C07D487/04 ,  C07D487/08 ,  C07D487/10 ,  C07D519/00

Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.

公开(公告)号：US20110092474A1

公开(公告)日：2011-04-21

申请号：US12997567

申请日：2009-06-11

Applicant: Hui Cai ,  Frank Chavez ,  Paul J. Dunford ,  Andrew J. Greenspan ,  Steven P. Meduna ,  Jorge A. Quiroz ,  Brad M. Savall ,  Kevin L. Tays ,  Robin L. Thurmond ,  Jianmei Wei ,  Ronald L. Wolin ,  Xiaohu Zhang

Inventor： Hui Cai ,  Frank Chavez ,  Paul J. Dunford ,  Andrew J. Greenspan ,  Steven P. Meduna ,  Jorge A. Quiroz ,  Brad M. Savall ,  Kevin L. Tays ,  Robin L. Thurmond ,  Jianmei Wei ,  Ronald L. Wolin ,  Xiaohu Zhang

IPC: A61K31/4439 ,  C07D401/04 ,  C07D405/14 ,  A61K31/496 ,  C07D403/04 ,  A61K31/506 ,  C07D401/14 ,  A61K31/501 ,  C07D487/04 ,  A61K31/551 ,  A61K31/444 ,  C07D237/20 ,  A61K31/50 ,  A61P29/00 ,  A61P37/08 ,  A61P17/00 ,  A61P37/06 ,  A61P37/04 ,  A61P11/06 ,  A61P9/10 ,  A61P25/00 ,  A61P27/02 ,  A61P1/00 ,  A61P17/06 ,  A61P17/04 ,  A61P11/00 ,  A61P3/10 ,  A61P13/12 ,  A61P7/06 ,  A61P1/16 ,  A61P25/24 ,  A61P25/18 ,  A61P25/22 ,  A61P25/04

CPC classification number: C07D213/74 ,  A61K31/44 ,  A61K31/50 ,  C07D237/20 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D405/12 ,  C07D405/14 ,  C07D487/04

Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.

Abstract translation: 可用作H 4受体调节剂的二氨基 - 吡啶，嘧啶和哒嗪化合物，以及用于治疗H4受体活性介导的疾病状态，病症和病症的药物组合物和方法，例如过敏，哮喘，自身免疫性疾病和 瘙痒症

公开(公告)号：US07772236B2

公开(公告)日：2010-08-10

申请号：US12220539

申请日：2008-07-24

Applicant: Mary Pat Beavers ,  J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Darin J. Gustin ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Kevin L. Tays ,  Jianmei Wei

Inventor： Mary Pat Beavers ,  J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Darin J. Gustin ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Kevin L. Tays ,  Jianmei Wei

IPC: A61K31/497 ,  A61K31/24 ,  A61K31/505

CPC classification number: C07D231/12 ,  C07D471/04

Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.

Abstract translation: 取代的吡唑，其制备方法，含有它们的组合物，以及使用它们来治疗例如由组织蛋白酶S介导的自身免疫疾病的方法。

公开(公告)号：US07645758B2

公开(公告)日：2010-01-12

申请号：US11735306

申请日：2007-04-13

Applicant: Hui Cai ,  Nicholas I. Carruthers ,  Curt A. Dvorak ,  James P. Edwards ,  Annette K. Kwok ,  Jianmei Wei

Inventor： Hui Cai ,  Nicholas I. Carruthers ,  Curt A. Dvorak ,  James P. Edwards ,  Annette K. Kwok ,  Jianmei Wei

IPC: C07D241/04 ,  A61K31/497 ,  C07D403/00

CPC classification number: C07D491/04 ,  C07D495/04

Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.

Abstract translation: 公开了某些噻吩并吡喃基和呋喃并吡咯基化合物可用于治疗或预防由组胺H 4受体介导的病症和病症，包括过敏性鼻炎。

公开(公告)号：US07388011B2

公开(公告)日：2008-06-17

申请号：US11517171

申请日：2006-09-07

Applicant: Mary Pat Beavers ,  J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Darin J. Gustin ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Kevin L. Tays ,  Jianmei Wei

Inventor： Mary Pat Beavers ,  J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Darin J. Gustin ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Kevin L. Tays ,  Jianmei Wei

IPC: A61K31/495 ,  C07D471/04

CPC classification number: C07D231/12 ,  C07D471/04

Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.

Abstract translation: 取代的吡唑，其制备方法，含有它们的组合物，以及使用它们来治疗例如由组织蛋白酶S介导的自身免疫性疾病的方法。

公开(公告)号：US07332494B2

公开(公告)日：2008-02-19

申请号：US10075673

申请日：2002-02-13

Applicant: J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Yin Gu ,  Darin J. Gustin ,  Lars Karlsson ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Siquan Sun ,  Kevin L. Tays ,  Robin L. Thurmond ,  Jianmei Wei

Inventor： J. Guy Breitenbucher ,  Hui Cai ,  James P. Edwards ,  Cheryl A. Grice ,  Yin Gu ,  Darin J. Gustin ,  Lars Karlsson ,  Haripada Khatuya ,  Steven P. Meduna ,  Barbara A. Pio ,  Siquan Sun ,  Kevin L. Tays ,  Robin L. Thurmond ,  Jianmei Wei

IPC: A61K31/497 ,  A61K31/50 ,  A61K31/53 ,  A61K31/505

CPC classification number: C07D231/12 ,  C07D471/04

Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.

Abstract translation: 一种使用取代的吡唑治疗过敏性疾病（包括特应性过敏症状）的方法。

公开(公告)号：US20070185131A1

公开(公告)日：2007-08-09

申请号：US11735311

申请日：2007-04-13

Applicant: Hui Cai ,  Nicholas Carruthers ,  Curt Dvorak ,  James Edwards ,  Annette Kwok ,  Jianmei Wei

Inventor： Hui Cai ,  Nicholas Carruthers ,  Curt Dvorak ,  James Edwards ,  Annette Kwok ,  Jianmei Wei

IPC: A61K31/496 ,  C07D491/02

CPC classification number: C07D491/04 ,  C07D495/04

Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.

Abstract translation: 公开了某些噻吩并吡喃基和呋喃并吡咯基化合物可用于治疗或预防由组胺H 4受体介导的病症和病症，包括过敏性鼻炎。

公开(公告)号：US20070004755A1

公开(公告)日：2007-01-04

申请号：US11517145

申请日：2006-09-07

Applicant: Mary Beavers ,  J. Breitenbucher ,  Hui Cai ,  James Edwards ,  Cheryl Grice ,  Darin Gustin ,  Haripada Khatuya ,  Steven Meduna ,  Barbara Pio ,  Kevin Tays ,  Jianmei Wei

Inventor： Mary Beavers ,  J. Breitenbucher ,  Hui Cai ,  James Edwards ,  Cheryl Grice ,  Darin Gustin ,  Haripada Khatuya ,  Steven Meduna ,  Barbara Pio ,  Kevin Tays ,  Jianmei Wei

IPC: A61K31/496 ,  C07D403/02

CPC classification number: C07D231/12 ,  C07D471/04

Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.

公开(公告)号：US20050245576A1

公开(公告)日：2005-11-03

申请号：US11174077

申请日：2005-06-30

Applicant: Christopher Butler ,  Hui Cai ,  James Edwards ,  Cheryl Grice ,  Darin Gustin ,  Haripada Khatuya ,  Steven Meduna ,  Barbara Pio ,  Clark Sehon ,  Kevin Tays ,  Jianmei Wei

Inventor： Christopher Butler ,  Hui Cai ,  James Edwards ,  Cheryl Grice ,  Darin Gustin ,  Haripada Khatuya ,  Steven Meduna ,  Barbara Pio ,  Clark Sehon ,  Kevin Tays ,  Jianmei Wei

IPC: C07D401/14 ,  A61K31/275 ,  A61K31/4155 ,  A61K31/437 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/517 ,  A61K31/5377 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/549 ,  A61K31/55 ,  A61P11/06 ,  A61P29/00 ,  A61P37/06 ,  A61P43/00 ,  C07D413/14 ,  C07D471/04 ,  C07D471/14 ,  C07D519/00 ,  C07D43/02

CPC classification number: C07D413/14 ,  A61K31/275 ,  A61K31/4155 ,  A61K31/454 ,  A61K31/495 ,  A61K31/55 ,  C07D471/04 ,  C07D471/14

Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.