发明申请
- 专利标题: Small Peptides And Methods For Inhibiting The Mucous Release Into Airways
- 专利标题(中): 小肽和抑制粘膜释放入气道的方法
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申请号: US11942202申请日: 2007-11-19
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公开(公告)号: US20080214475A1公开(公告)日: 2008-09-04
- 发明人: John C. Houck , James Clagett , Mary MacDonald
- 申请人: John C. Houck , James Clagett , Mary MacDonald
- 主分类号: A61K38/06
- IPC分类号: A61K38/06 ; A61K38/07 ; A61P11/00
摘要:
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
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