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发明申请
US20080214526A1 Macrocyclic Compounds and Compositions Useful as Bace Inhibitors 失效
用作阻止剂的大环化合物和组合物

Macrocyclic Compounds and Compositions Useful as Bace Inhibitors
摘要：
The invention relates to novel macrocyclic compounds of the formula in which R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
摘要（中）：

本发明涉及下式的新型大环化合物，其中R 1，R 3，V 1，V 2， X，X 1，X 2，Y，Z，Ar，AA和n如说明书中所定义，大环中包括的环原子数为14 ，15,16,17或18，以游离碱形式或以酸加成盐形式，用于制备，用作药物和包含它们的药物。

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