发明申请
- 专利标题： Compounds and Compositions as Protein Kinase Inhibitors
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
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申请号： US11718886申请日： 2005-11-07
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公开(公告)号： US20080221192A1公开(公告)日： 2008-09-11
- 发明人: Yongqin Wan , Yuan Mi , Yi Fan , Dai Cheng , Yi Liu , Nathanael S. Gray , Pamela Albaugh
- 申请人： Yongqin Wan , Yuan Mi , Yi Fan , Dai Cheng , Yi Liu , Nathanael S. Gray , Pamela Albaugh
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 国际申请： PCT/US05/40372 WO 20051107
- 主分类号： A61P43/00
- IPC分类号： A61P43/00 ; C07D209/04 ; A61K31/404
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC kinases.
公开/授权文献
- US08101608B2 Compounds and compositions as protein kinase inhibitors 公开/授权日：2012-01-24
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