发明申请
- 专利标题: Primer, primer set, and nucleic acid amplification method and mutation detection method using the same
- 专利标题(中): 引物,引物组和核酸扩增方法及使用其的突变检测方法
-
申请号: US12075198申请日: 2008-03-10
-
公开(公告)号: US20080227104A1公开(公告)日: 2008-09-18
- 发明人: Yoshihide Hayashizaki , Akimitsu Okamoto , Alexander Lezhava , Yasushi Kogo
- 申请人: Yoshihide Hayashizaki , Akimitsu Okamoto , Alexander Lezhava , Yasushi Kogo
- 申请人地址: JP Wako-shi JP Yokohama-shi
- 专利权人: RIKEN,KABUSHIKI KAISHA DNAFORM
- 当前专利权人: RIKEN,KABUSHIKI KAISHA DNAFORM
- 当前专利权人地址: JP Wako-shi JP Yokohama-shi
- 优先权: JP2007-059921 20070309; JP2007-246253 20070921; JP2007-248257 20070925; JP2007-335352 20071226; JP2008-035325 20080215
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/00 ; C12P19/34 ; C12N9/10
摘要:
The present invention provides a primer that effectively can detect, for example, the double helix structure of a nucleic acid. The primer is a labeled nucleic acid containing at least one structure represented by the following formula (16), where B is an atomic group having a nucleobase skeleton, E is an atomic group having a deoxyribose skeleton, a ribose skeleton, or a structure derived from either one of them, or an atomic group having a peptide structure or a peptoid structure, and Z11 and Z12 are each an atomic group that exhibits fluorescence and are identical to or different from each other.
公开/授权文献
信息查询