发明申请
- 专利标题: Medical devices having antimicrobial coatings thereon
- 专利标题(中): 具有抗微生物涂层的医疗装置
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申请号: US12214321申请日: 2008-06-18
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公开(公告)号: US20080260804A1公开(公告)日: 2008-10-23
- 发明人: Carol Ann Morris , Manal M. Gabriel , Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Marcia Kay Ash , Fiona Patricia Carney , Courtney Flem Morgan
- 申请人: Carol Ann Morris , Manal M. Gabriel , Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Marcia Kay Ash , Fiona Patricia Carney , Courtney Flem Morgan
- 主分类号: A01N25/34
- IPC分类号: A01N25/34 ; A01N33/12 ; A61K38/40 ; G01N19/02
摘要:
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.