发明申请
- 专利标题： Diagnosis and Treatment of Siglec-6 Associated Diseases
- 专利标题（中）： Siglec-6相关疾病的诊断与治疗
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申请号： US11629047申请日： 2005-06-09
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公开(公告)号： US20080267973A1公开(公告)日： 2008-10-30
- 发明人: Shen-Wu Wang , Guanghu Hu , Zhengbin Yao
- 申请人： Shen-Wu Wang , Guanghu Hu , Zhengbin Yao
- 专利权人： Genetech, Inc.
- 当前专利权人： Genetech, Inc.
- 国际申请： PCT/US2005/020271 WO 20050609
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28 ; C07H21/04 ; A61P11/06 ; C12Q1/02 ; G01N33/566 ; C12Q1/68 ; G01N33/567 ; C12N5/06
摘要：
The present invention relates to agonists, antagonists, and other molecules that specifically bind SIGLEC-6 on mast cells, their use in the treatment of asthma and other SIGLEC-6 mediated diseases or disorders, methods of diagnosing such diseases or disorders, and methods of screening for candidate compounds capable of modulating SIGLEC-6 activity in mast cells. The present invention also relates to the diagnosis and treatment of B-cell related disorders using compounds that bind and/or modulate SIGLEC-6.
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