发明申请
- 专利标题： Tyrosine kinase inhibitors
- 专利标题（中）： 酪氨酸激酶抑制剂
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申请号： US12148649申请日： 2008-04-21
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公开(公告)号： US20080274107A1公开(公告)日： 2008-11-06
- 发明人: Mark E. Fraley , Kenneth L. Arrington , Mark T. Bilodeau , George D. Hartman , William F. Hoffman , Yuntae Kim , Randall W. Hungate
- 申请人： Mark E. Fraley , Kenneth L. Arrington , Mark T. Bilodeau , George D. Hartman , William F. Hoffman , Yuntae Kim , Randall W. Hungate
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07D215/20 ; A61K31/337 ; A61K31/445 ; A61K31/47 ; A61P43/00
摘要：
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.
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