发明申请
- 专利标题: Process for Preparing Substituted Anisidines
- 专利标题(中): 制备取代苯胺的方法
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申请号: US12092454申请日: 2006-11-01
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公开(公告)号: US20080293972A1公开(公告)日: 2008-11-27
- 发明人: Fabrice Gallou , Heewon Lee , Chris Hugh Senanayake , Jinhua J. Song , Zhulin Tan , Jinghua Xu , Nathan K. Yee
- 申请人: Fabrice Gallou , Heewon Lee , Chris Hugh Senanayake , Jinhua J. Song , Zhulin Tan , Jinghua Xu , Nathan K. Yee
- 国际申请: PCT/US2006/042845 WO 20061101
- 主分类号: C07C213/02
- IPC分类号: C07C213/02 ; C07C251/44
摘要:
Disclosed is a process for preparing substituted anisidines of formula I starting from substituted cyclic hydroxy-ketones II via aromatization through a substituted oxime intermediate IV in which R is C1-C6 alkyl or halogen, and Alk is C1-C6 alkyl. The substituted anisidines of formula I have been found to be useful as intermediates in the preparation of agents for the treatment of hepatitis C viral (HCV) infections.
公开/授权文献
- US07884246B2 Process for preparing substituted anisidines 公开/授权日:2011-02-08