发明申请
- 专利标题: BUTYLPHTHALIDE SOFT GEL CAPSULE AND ITS PREPARATION PROCEDURE
- 专利标题(中): 丁二醇软胶囊及其制备方法
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申请号: US12195360申请日: 2008-08-20
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公开(公告)号: US20080305163A1公开(公告)日: 2008-12-11
- 发明人: Jianqing Li , Min Bai , Wenmin Guo , Surui Chen , Liyun Liu , Guirong Zhou
- 申请人: Jianqing Li , Min Bai , Wenmin Guo , Surui Chen , Liyun Liu , Guirong Zhou
- 优先权: CN200310119336.1 20031205
- 主分类号: A61K31/365
- IPC分类号: A61K31/365 ; A61K9/48 ; A61P7/02
摘要:
The present invention discloses a novel dosage form of butylphthalide soft capsule and its preparation procedure. Butylphthalide soft capsule is composed of a coating material and a drug-containing oil. The drug-containing oil is basically composed of butylphthalide and diluent—vegetable oil, wherein the weight ratio of butylphthalide to oil ranges from 1:0˜10. The coating material is composed of gelatin, plasticizer and water, wherein the weight ratio of gelatin to plasticizer to water is in the range of 1:0.2˜0.4:0.8˜0.3. The butylphthalide soft capsule described in this invention can mask the strong and specific flavor of butylphthalide, and overcome the difficulties associated with formulating oily active agents into other oral preparations. The disintegration time of the soft capsule complies with the requirement of Pharmacopoeia of P.R. China.
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