发明申请
US20090018084A1 METHODS OF RESTORING COGNITIVE ABILITY USING NON-PEPTIDIC COMPOUNDS
有权
使用非特异性化合物恢复认知能力的方法
- 专利标题: METHODS OF RESTORING COGNITIVE ABILITY USING NON-PEPTIDIC COMPOUNDS
- 专利标题(中): 使用非特异性化合物恢复认知能力的方法
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申请号: US11777266申请日: 2007-07-12
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公开(公告)号: US20090018084A1公开(公告)日: 2009-01-15
- 发明人: Grant A. KRAFFT , Todd Pray , William F. Goure
- 申请人: Grant A. KRAFFT , Todd Pray , William F. Goure
- 专利权人: Acumen Pharmaceuticals, Inc.
- 当前专利权人: Acumen Pharmaceuticals, Inc.
- 主分类号: A61K38/08
- IPC分类号: A61K38/08 ; A61K38/00 ; A61P25/28
摘要:
Disclosed are methods of enhancing cognitive impairment in a patient wherein the cognitive impairment is due to ADDL neurotoxicity. The methods employ non-peptidic compounds having a molecular weight of less than 1000 and which can antagonize against formation of neurotoxic ADDLs from Aβ1-42 monomers.
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