发明申请
- 专利标题： Compositions and methods for modulating sirtuin activity
- 专利标题（中）： 调节sirtuin活性的组合物和方法
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申请号： US12100080申请日： 2008-04-09
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公开(公告)号： US20090069559A1公开(公告)日： 2009-03-12
- 发明人: Aleksey G. Kazantsev
- 申请人： Aleksey G. Kazantsev
- 专利权人： The General Hospital Corporation
- 当前专利权人： The General Hospital Corporation
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D401/10 ; C07D413/10
摘要：
The present invention is based, in part, on our discovery of compounds that inhibit an activity of a sirtuin (e.g., compounds that inhibit or preferentially inhibit an activity of SIRT2) and are therefore believed useful in the treatment or prevention of diseases associated with sirtuin activity. These diseases include, but are not limited to, neurological disorders such as Parkinson's Disease (PD).
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