发明申请
- 专利标题: PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES
- 专利标题(中): 含有硫酸衍生物的药物组合物
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申请号: US12264000申请日: 2008-11-03
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公开(公告)号: US20090076140A1公开(公告)日: 2009-03-19
- 发明人: Beatriz Maria Banfi Tosi , Guillermo Gimenez Gallego , Serafin Valverde Lopez , Rosa Maria Lozano Puerto , Pedro Sanchez Cuevas
- 申请人: Beatriz Maria Banfi Tosi , Guillermo Gimenez Gallego , Serafin Valverde Lopez , Rosa Maria Lozano Puerto , Pedro Sanchez Cuevas
- 申请人地址: ES Alcobendas ES Madrid ES Madrid
- 专利权人: ITALFARMACO, S. A.,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS,INSTITUTO MADRILENO DE LA SALUD
- 当前专利权人: ITALFARMACO, S. A.,CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS,INSTITUTO MADRILENO DE LA SALUD
- 当前专利权人地址: ES Alcobendas ES Madrid ES Madrid
- 优先权: ES200300563 20030307
- 主分类号: A61K31/255
- IPC分类号: A61K31/255 ; A61P19/02 ; A61P17/06 ; A61P3/04 ; A61P9/10
摘要:
A naphthalenesulfonic acid or quinolinesulfonic acid of formula (I), wherein A is N or a CR8 formula group, where R8 is H, OH, NR10OR11, independently from one another, where R10 and R11 represent H or C1-C6 alkyl or a group of formula NH—CO—R12, where R12 is C1-C6 alkyl or C6-C10 aryl; R1 and R2 represent H or SO3R9, independently from one another, where R9 is H, ammonium or a cation of an alkali or alkaline-earth metal; R3 is H or OH; and R4, R5, R6 and R7 represent H, an NR10R11 or NH—CO—R12 group, independently from one another; on the condition that (i) at least one of R1 or R2 is SO3R9, and (ii) at least one of R4, R5, R6 or R7 is an NR10R11 or NH—CO—R12 group, or their pharmaceutically acceptable salts; and a pharmaceutically acceptable excipient.
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