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1.Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of psoriasis 有权
标题翻译: 使用2,5-二羟基苯化合物及其衍生物治疗牛皮癣公开(公告)号:US08530454B2
公开(公告)日:2013-09-10
申请号:US13166569
申请日:2011-06-22
申请人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Javier Angulo Frutos , Serafin Valverde Lopez , Atonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorman , Javier Angulo Frutos , Serafin Valverde Lopez , Atonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/185 , A61P17/12 , A61P17/06
CPC分类号: A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, psoriasis.
摘要翻译: 本发明涉及式(I)的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂化物,异构体或前药在治疗和/或预防银屑病方面的用途。
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2.Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer 有权
标题翻译: 使用2,5-二羟基苯化合物和衍生物治疗皮肤癌公开(公告)号:US20120087904A1
公开(公告)日:2012-04-12
申请号:US13326778
申请日:2011-12-15
申请人: Pedro Cuevas Sànchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sànchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/60 , A61K31/185 , A61P35/00 , A61K31/437 , A61K31/196 , A61K38/46 , A61K31/513 , A61K31/202 , A61K31/675 , A61K31/22 , A61P31/00 , A61P25/04 , A61P37/02 , A61P23/00 , A61P29/00 , A61K31/19
CPC分类号: A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, skin cancer.
摘要翻译: 本发明涉及式(I)的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂化物,异构体或前药在治疗和/或预防皮肤癌中的用途。
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3.USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF ROSACEA 有权
标题翻译: 使用2,5-二羟基苯乙烯化合物和衍生物用于治疗ROSACEA公开(公告)号:US20110237555A1
公开(公告)日:2011-09-29
申请号:US13154164
申请日:2011-06-06
申请人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/60 , A61K31/222 , A61K31/255 , A61K31/225 , A61K31/192 , A61K31/56 , A61K31/4168 , A61P17/00 , A61P31/00 , A61P27/02
CPC分类号: A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea.
摘要翻译: 本发明涉及式(I)的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂合物,异构体或前药用于治疗和/或预防酒渣肠炎的用途。
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4.USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF ARTHRITIS AND PAIN 审中-公开
标题翻译: 使用2,5-二羟基苯甲醛衍生物治疗神经痛和疼痛公开(公告)号:US20110152222A1
公开(公告)日:2011-06-23
申请号:US12377837
申请日:2007-08-15
IPC分类号: A61K31/216 , C07C309/60 , C07C309/58 , C07C309/77 , C07C69/013 , C07C69/732 , C07C59/48 , A61K31/225 , A61K31/255 , A61K31/192 , A61K31/56 , A61K31/606 , A61P19/02 , A61P29/00 , A61P17/06
CPC分类号: A61K31/10 , A61K31/192 , A61K31/60 , A61K31/618 , Y02A50/409
摘要: The present invention relates to the use of a compound of Formula (I′″) or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of arthritis and pain.
摘要翻译: 本发明涉及式(I'“)化合物或其药学上可接受的盐或溶剂合物,异构体或前药在制备用于治疗和/或预防关节炎和疼痛的药物中的用途。
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5.Use of 2,5-Dihydroxybenzene Compounds and Derivatives for the Treatment of Hematological Dyscrasias and Cancer of an Organ 有权
标题翻译: 使用2,5-二羟基苯化合物和衍生物治疗血液性D摩擦症和器官癌公开(公告)号:US20080125486A1
公开(公告)日:2008-05-29
申请号:US11839525
申请日:2007-08-15
申请人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez
发明人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez
IPC分类号: A61K31/22 , A61K31/192 , A61K31/185
CPC分类号: A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00
摘要: The present invention refers to the use of the compound of Formula (I′) or pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of hematological dyscrasias, including myelodisplastic syndromes (MDSs) and for improving the efficacy of chemotherapy, radiation therapy and/or cancer immunotherapy. In addition, it relates to the use of a compound of formula (I″) for the treatment and/or prophylaxis of cancer of an organ.
摘要翻译: 本发明涉及式(I')化合物或其药学上可接受的盐,溶剂合物,异构体或前体药物在治疗和/或预防血液恶化症中的用途,包括骨髓增生异常综合征(MDS)和用于改善功效 的化疗,放射治疗和/或癌症免疫治疗。 此外,它涉及式(I“)化合物用于治疗和/或预防器官癌症的用途。
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6.Use of 2,5-Dihydroxybenzene Derivatives for Treating Actinic Keratosis 审中-公开
标题翻译: 2,5-二羟基苯衍生物用于治疗肌动蛋白性角化病的用途公开(公告)号:US20080125485A1
公开(公告)日:2008-05-29
申请号:US11839508
申请日:2007-08-15
申请人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/22 , A61K31/192 , A61K31/185
CPC分类号: A61K31/185 , A61B17/320708 , A61K31/192 , A61K31/216 , A61K31/22 , A61K31/56 , A61K31/59 , A61K31/60 , A61K45/06 , A61M37/00 , A61N5/062 , C07C309/42 , C07C309/60
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or phrophylactic treatment of, inter alia, actinic keratosis.
摘要翻译: 本发明涉及由式(I)表示的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂合物,异构体或前药用于治疗和/或药物治疗尤其是光化性角化病的用途。
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7.
公开(公告)号:US20080114075A1
公开(公告)日:2008-05-15
申请号:US11839512
申请日:2007-08-15
申请人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sanchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
CPC分类号: A61K31/185 , A61K8/368 , A61K8/466 , A61K31/10 , A61K31/192 , A61K31/222 , A61K31/225 , A61K31/60 , A61K31/618 , A61K45/06 , A61Q17/04 , A61Q19/08
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, dermatitis.
摘要翻译: 本发明涉及由式(I)表示的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂合物,异构体或前药用于治疗和/或预防性治疗特别是皮炎的用途。
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公开(公告)号:US08815836B2
公开(公告)日:2014-08-26
申请号:US13209803
申请日:2011-08-15
申请人: Pedro Cueva Sànchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorman , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cueva Sànchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorman , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A01N37/36 , A01N45/00 , A61K31/56 , A01N41/02 , A61K31/255 , A01N37/10 , A61K31/235 , A01N37/02 , A61K31/22 , A61K31/60 , A61K31/10 , A61K31/618 , A61K31/192
CPC分类号: A61K31/185 , A61K8/368 , A61K8/466 , A61K31/10 , A61K31/192 , A61K31/222 , A61K31/225 , A61K31/60 , A61K31/618 , A61K45/06 , A61Q17/04 , A61Q19/08
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, dermatitis.
摘要翻译: 本发明涉及由式(I)表示的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂合物,异构体或前药用于治疗和/或预防性治疗特别是皮炎的用途。
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公开(公告)号:US20120087947A1
公开(公告)日:2012-04-12
申请号:US13209803
申请日:2011-08-15
申请人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/255 , A61K31/192 , A61K38/46 , A61K31/675 , A61K31/56 , A61K31/436 , A61K31/606 , A61P17/00 , A61P31/00 , A61P29/00 , A61P37/02 , A61P37/06 , A61P23/00 , A61P35/00 , A61K31/235
CPC分类号: A61K31/185 , A61K8/368 , A61K8/466 , A61K31/10 , A61K31/192 , A61K31/222 , A61K31/225 , A61K31/60 , A61K31/618 , A61K45/06 , A61Q17/04 , A61Q19/08
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, dermatitis.
摘要翻译: 本发明涉及由式(I)表示的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂合物,异构体或前药用于治疗和/或预防性治疗特别是皮炎的用途。
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10.USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS 有权
标题翻译: 使用2,5-二羟基苯甲酸衍生物进行治疗药物治疗公开(公告)号:US20110257264A1
公开(公告)日:2011-10-20
申请号:US12946742
申请日:2010-11-15
申请人: Pedro Cuevas S?nchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
发明人: Pedro Cuevas S?nchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto
IPC分类号: A61K31/255 , A61K31/235 , A61K8/37 , A61K31/192 , A61P3/04 , A61K8/365 , A61P17/12 , A61P17/00 , A61Q19/08 , A61P31/12 , A61K8/46 , A61K8/368
CPC分类号: A61K31/185 , A61B17/320708 , A61K31/192 , A61K31/216 , A61K31/22 , A61K31/56 , A61K31/59 , A61K31/60 , A61K45/06 , A61M37/00 , A61N5/062 , C07C309/42 , C07C309/60
摘要: The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, actinic keratosis.
摘要翻译: 本发明涉及由式(I)表示的2,5-二羟基苯衍生物或其药学上可接受的盐,溶剂化物,异构体或前药用于治疗和/或预防性治疗光化性角化病的用途。
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